False measurement of glycated hemoglobin in patients without hemoglobin A

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Glycated hemoglobin in fractionated erythrocytes.

Erythrocytes were fractionated, by centrifugation, on the basis of cell density, which is proportional to cell age. Glycated hemoglobin (Hb A1c) in the fractionated cells was measured and compared with the Hb A1c in whole blood and with the fructosamine concentrations in plasma of normal and diabetic subjects. In normal subjects, Hb A1c increased according to the age of the erythrocytes, but hy...

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ژورنال

عنوان ژورنال: Bioscience Reports

سال: 2019

ISSN: 0144-8463,1573-4935

DOI: 10.1042/bsr20180128